![]() ![]() For this reason, correct diagnosis of this condition is important. 50% of first-degree relatives will inherit the same mutation, giving them a greater than 95% lifetime risk of developing MODY themselves. The prevalence is 70–110 per million people. MODY is the final diagnosis in 1%–2% of people initially diagnosed with diabetes. Robert Tattersall and Stefan Fajans initially identified the phenomenon known as maturity onset diabetes of the young in a classic study published in the journal Diabetes in 1975. GCK-MODY ( MODY 2) and HNF1A-MODY ( MODY 3) are the most common forms. While the more common types of diabetes (especially type 1 and type 2) involve more complex combinations of causes involving multiple genes and environmental factors, each forms of MODY are caused by changes to a single gene (monogenic). Along with neonatal diabetes, MODY is a form of the conditions known as monogenic diabetes. ![]() Maturity-onset diabetes of the young ( MODY) refers to any of several hereditary forms of diabetes mellitus caused by mutations in an autosomal dominant gene disrupting insulin production. Medical condition Maturity-onset diabetes of the young (MODY) ![]()
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